The major focus of the preclinical research program of the Laboratory
for Applied Radiobiology, Department of Radiation Oncology,University Hospital
Zurich, is "Combined Treatment Modality". This program includes
different aspects of translational research in the field of radiobiology
investigating the cellular and tumoral response on the molecular, cellular and
in vivo level to ionizing radiation alone and in combination with classical
chemotherapeutical and novel pharmacological agents.
Founded in 1995 our laboratory is headed by Prof. Dr. Martin Pruschy,
PhD and is completely integrated in both the preclinical research divisions of
the head quarters of the University Hospital Zurich and in the clinical
premises of the Department of Radiation Oncology.
It is this special environment that contributes to the translational
spirit of our laboratory. Several PhD-candidates, MD- and PhD-Post-Doctoral
fellows, and a highly motivated lab technician complete our team.
The research activities consist of 3 major topics that investigate the cellular response to ionizing radiation alone and in combination with classical chemotherapeutical or novel pharmacological agents. A major goal is to understand treatment resistance on the molecular and cellular level and to translate novel combined treatment modalities into a clinical environment.